BMR 617: Statistical Techniques for the Biomedical Sciences

This course is intended for students in the Biomedical Research Ph.D. program. Students in this course will learn the basics of data exploration, presentation, and analysis suitable for biomedical researchers. We will focus on interpretation of data, and on presenting results in a form suitable for publication in peer-reviewed manuscripts.

Class time:
Monday, Wednesday, and Friday 10-10:50 am
Class meeting room:
Byrd Biotechnology and Science Center Room 102

Course director and instructor: James Denvir, Ph.D.
Office:
BBSC 336R
Phone:
304-696-7327

Course instructor: Andrew Nato, Ph.D.
Office:
BBSC 336M
Phone:
304-696-3562
This course will use online materials; there is no text book. Class time will typically involve students sharing material they about which they were confused or had questions, with discussion, and a preview by the instructor(s) of the material to be covered before the next class.
Students will use the R statistical computing environment for data analysis and visualization. For help with R and RStudio, use the R Resources button on the navigation bar, in addition to material provided in class.
DateLectureR Code
January 11th 2023 Installing and Intro to R intro.R
January 13th 2023 Types of variable types.R
January 18th 2023 Distributions MeanMedianSpread.R
January 20th 2023 The Normal Distribution NormalDistribution.R
January 23rd 2023 Data Wrangling DataWrangling.R
January 25th 2023 Introduction to Graphing with ggplot2 GraphincCQ.R
January 27th2023 Relative and Attributable Risk R_A_Risks.R
January 30th 2023 Correlation Correlation.R
February 1st 2023 Color in ggplot Color.R
February 3rd 2023 Review of Part 1
February 8th 2023 Probability
February 10th 2023 Samples and the Central Limit Theorem error_bars.R
February 13th 2023 Point estimation of the mean and introduction to confidence intervals IntroConfIntervals.R
February 15th 2023 Confidence Intervals
Confidence Intervals for Proportions
ConfidenceIntervals.R
ConfidenceIntervalsProportions.R
February 17th 2023 Hypothesis Testing HypothesisTesting.R
February 20th 2023 Hypothesis Testing for a Single Proportion
Matrices, data frames, and tables in R

MatricesDataFramesTables.R
February 22nd 2023 Comparing Proportions ComparingProportions.R
February 24th 2023 Hypothesis Testing for Population Mean HypothesisTestingPopulationMean.R
February 27th 2023 Inference: Two-Class t-test TwoSample_t-test.R
March 1st 2023 Inference: Paired T-test PairedTTest.R
March 3rd Review 2
March 20th One Way ANOVA
March 22nd Two Way ANOVA
March 24th Exponential Growth
Normalization
ExponentialGrowth.R
Normalization.R
March 27th Linear Regression LinRegCovid.R
March 29th Multiple Linear Regression MultLinReg.R
March 31st Linear Models LinModels.R
April 3rd Sample Size and Power Exploration in R
April 5th Review 3
April 7th Real Time PCR Data PCR.R
April 10th Writing statistics sections for journal articles Cholesterol.R
April 14th R Notebooks Cholesterol.Rmd
April 17th Multiple Hypothesis Testing MultipleHypothesisTesting.R
AssignmentDue DateModel solutionR code
Creating an R ScriptJanuary 13th, 2023
Computing measures of central tendency and spreadJanuary 20th, 2023
Comparing data sets to the normal distributionJanuary 23rd
Exploring box plots with ggplot2January 27th
Bar graphs with error barsFebruary 16th
Installing R and R studio:
  • Home page and download for R (install R first from here)
  • R Studio (install the free version of R Studio from here, after installing R)
These are some (of very many) free online tutorials available which make good background reading: